10
20
20
CMR derived PCWP: 0 mmHg
170
70
70
50
60
70
60
70
Calculated Value: 0
170
70
70
Body Surface Area (BSA): 0 m²
Cardiac Magnetic Resonance (CMR) derived Left Ventricular Filling Pressure (LVFP) is a significant tool in the assessment and prognosis of heart failure (HF). Studies have shown that elevated CMR-derived LVFP is strongly associated with symptoms and signs of HF, such as pleural effusions, orthopnoea, lower limb oedema, and breathlessness.[1] Furthermore, raised CMR-derived LVFP is independently associated with subsequent HF hospitalization and major adverse cardiovascular events (MACE).[1]
CMR can estimate LVFP in patients with suspected HF, and this CMR-modelled LVFP has been shown to have prognostic power.[2] It was found to be superior to transthoracic echocardiography in classifying patients as having normal or raised filling pressures and was associated with an increased risk of death.[2]
In addition to its role in HF, CMR-derived LVFP can also be used to measure acute and dynamic changes in preloading conditions on the left ventricle during adenosine administered first-pass perfusion CMR, where it has been observed to rise significantly.[3]
In conclusion, CMR-derived LVFP is a valuable tool in the diagnosis, management, and prognosis of HF and other cardiovascular conditions. It provides critical insights into the patient's condition and can guide therapeutic decisions.
References
1. Cardiac Magnetic Resonance Left Ventricular Filling Pressure Is Linked to Symptoms, Signs and Prognosis in Heart Failure.
Grafton-Clarke C, Garg P, Swift AJ, et al.
ESC Heart Failure. 2023;. doi:10.1002/ehf2.14499.
2. Cardiac Magnetic Resonance Identifies Raised Left Ventricular Filling Pressure: Prognostic Implications.
Garg P, Gosling R, Swoboda P, et al.
European Heart Journal. 2022;43(26):2511-2522. doi:10.1093/eurheartj/ehac207.
3. An Acute Increase in Left Atrial Volume and Left Ventricular Filling Pressure During Adenosine Administered Myocardial Hyperaemia: CMR First-Pass Perfusion Study.
Garg P, Javed W, Assadi H, et al.
BMC Cardiovascular Disorders. 2023;23(1):246. doi:10.1186/s12872-023-03230-x.
CMR can estimate LVFP in patients with suspected HF, and this CMR-modelled LVFP has been shown to have prognostic power.[2] It was found to be superior to transthoracic echocardiography in classifying patients as having normal or raised filling pressures and was associated with an increased risk of death.[2]
In addition to its role in HF, CMR-derived LVFP can also be used to measure acute and dynamic changes in preloading conditions on the left ventricle during adenosine administered first-pass perfusion CMR, where it has been observed to rise significantly.[3]
In conclusion, CMR-derived LVFP is a valuable tool in the diagnosis, management, and prognosis of HF and other cardiovascular conditions. It provides critical insights into the patient's condition and can guide therapeutic decisions.
References
1. Cardiac Magnetic Resonance Left Ventricular Filling Pressure Is Linked to Symptoms, Signs and Prognosis in Heart Failure.
Grafton-Clarke C, Garg P, Swift AJ, et al.
ESC Heart Failure. 2023;. doi:10.1002/ehf2.14499.
2. Cardiac Magnetic Resonance Identifies Raised Left Ventricular Filling Pressure: Prognostic Implications.
Garg P, Gosling R, Swoboda P, et al.
European Heart Journal. 2022;43(26):2511-2522. doi:10.1093/eurheartj/ehac207.
3. An Acute Increase in Left Atrial Volume and Left Ventricular Filling Pressure During Adenosine Administered Myocardial Hyperaemia: CMR First-Pass Perfusion Study.
Garg P, Javed W, Assadi H, et al.
BMC Cardiovascular Disorders. 2023;23(1):246. doi:10.1186/s12872-023-03230-x.